thromboembolic
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anticoagulant (항응고제) 혈액의 응고를 막는 물질. Those administered for prophylaxis or
treatment of thromboembolic disorders are heparin, which inactivates thrombin and
several other clotting factors and which must be administered parenterally, and the oral
anticoagulants (warfarin, dicumarol, and congeners) which inhibit the hepatic synthesis
of vitamin K-dependent clotting factors. Anticoagulant solutions used for the
preservation of stored whole blood and blood fractions are acid citrate dextrose (ACD),
citrate phosphate dextrose (CPD), citrate phosphate dextrose-adenine (cPDA-1) and
heparin. Anticoagulants used to prevent clotting of blood specimens for laboratory
analysis are heparin and several substances that make calcium ions unavailable to the
clotting process, including EDTA (ethylenediaminetetraacetic acid), citrate, oxalate, and
fluoride.
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